Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23682
Gene Symbol: RAB38
RAB38 		0.110 GeneticVariation disease GWASDB Frontotemporal dementia and its subtypes: a genome-wide association study. 24943344 2014
Entrez Id: 56244
Gene Symbol: BTNL2
BTNL2 		0.110 GeneticVariation disease GWASDB Frontotemporal dementia and its subtypes: a genome-wide association study. 24943344 2014
Entrez Id: 3132
Gene Symbol: HLA-DRB9
HLA-DRB9 		0.100 GeneticVariation disease GWASDB Frontotemporal dementia and its subtypes: a genome-wide association study. 24943344 2014
Entrez Id: 101929163
Gene Symbol: TSBP1-AS1
TSBP1-AS1 		0.100 GeneticVariation disease GWASDB Frontotemporal dementia and its subtypes: a genome-wide association study. 24943344 2014
Entrez Id: 2896
Gene Symbol: GRN
GRN 		0.900 Biomarker disease GENOMICS_ENGLAND Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 17923627 2007
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.800 Biomarker disease GENOMICS_ENGLAND Identification of PSEN1 and PSEN2 gene mutations and variants in Turkish dementia patients. 22503161 2012
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.800 Biomarker disease GENOMICS_ENGLAND Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease. 26539891 2015
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.800 Biomarker disease GENOMICS_ENGLAND Rare causes of early-onset dystonia-parkinsonism with cognitive impairment: a de novo PSEN-1 mutation. 28664294 2017
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.800 Biomarker disease GENOMICS_ENGLAND The genetics of Alzheimer disease. 23028126 2012
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		0.700 Biomarker disease GENOMICS_ENGLAND Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations. 20697052 2010
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		0.700 Biomarker disease GENOMICS_ENGLAND TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. 18372902 2008
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		0.700 Biomarker disease GENOMICS_ENGLAND CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro. 17956895 2008
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		0.500 Biomarker disease GENOMICS_ENGLAND Lack of C9ORF72 coding mutations supports a gain of function for repeat expansions in amyotrophic lateral sclerosis. 23597494 2013
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		0.500 Biomarker disease GENOMICS_ENGLAND Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease. 25326098 2014
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		0.500 Biomarker disease GENOMICS_ENGLAND Parkinsonism, movement disorders and genetics in frontotemporal dementia. 26891767 2016
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT Segregation of a missense mutation in the microtubule-associated protein tau gene with familial frontotemporal dementia and parkinsonism. 9736786 1998
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes. 11278002 2001
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in Western Europe. 14517953 2003
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT Frontotemporal dementia with parkinsonism is often linked to chromosome 17 and is related to mutations in the MAPT gene. 15883319 2005
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT We report a Japanese family with early onset hereditary frontotemporal dementia and a novel missense mutation (Ser305Asn) in the tau gene. 10208578 1999
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT A novel L266V mutation of the tau gene causes frontotemporal dementia with a unique tau pathology. 12509859 2003
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.800 GeneticVariation disease UNIPROT An autosomal-dominantly form of frontotemporal dementia and parkinsonism linked to chromosome 17q21.2 (FTDP-17) was defined in 1996. 26086902 2015